Probably the best place to look first is the quickstart videos here: Piezography Getting Started Guides (Windows & Mac)
If you are on a Mac it’s pretty straight forward. On a PC, there may be a bug that just cropped up this weekend. If you are using P400 for Piezo on Windows you need to use the R2000 curve folder for it to work.
If you have specific questions about getting started feel free to ask them.