So far no problems but these things have not been fully tested.
Photoshop CC sometimes crashed when printing to epson printers. Epson is updating all of its printers even though it's more of an apple issue.
So far no problems other than intermittent crashes.
CC 2015.5 and lower do not work properly with Sierra.
I advise holding off on upgrading to ANY OS until is in the .2 or .3 stage.